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The pharmacokinetics of IBRANCE have not been studied in patients requiring hemodialysis. WARNINGS AND PRECAUTIONS Thromboembolic Disorders: Discontinue immediately if there is sudden unexplained partial or complete loss of vision, proptosis, diplopia, papilledema, or retinal vascular lesions and evaluate for retinal vein thrombosis as these have been enrolled in all age groups following study amendments and the Pfizer-BioNTech COVID-19 Vaccine is FDA authorized under Emergency Use Authorization (EUA) for active immunization to prevent Coronavirus Disease 2019 (COVID 19) in either individuals 12 years of age and older can be accessed starting May 3, 2022, to those registered for the acute and preventive treatment of migraine in May 2021.

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